Hailey-Hailey
Organoids, CRISPR, and a Shortcut to Therapies for Rare Blistering Diseases
Blistering skin diseases cause a great deal of ongoing suffering. Their characteristic surface wounds cause pain, itching, and infections, and conventional treatments, including topical and oral corticosteroids, provide temporary, limited relief. For autoimmune blistering diseases, like pemphigus vulgaris, monoclonal antibodies (e.g., rituximab) promise longer-lasting relief, while CAAR-T cell…