genetic risk factors

Pustular psoriasis is a group of inflammatory skin diseases characterized by visible, sterile pustules on inflamed skin. It appears in generalized and localized forms and can occur in patients with or without a history of psoriasis. Pustular psoriasis has distinct genetic risk factors, inflammatory profile, and response to treatment compared to psoriasis. Thus, it may be its own unique disease. PPP is characterized by sterile pustules on the palms and soles. There is no consensus on optimal treatment , although acitretin, methotrexate, and phototherapy are among the more common treatments.