Tregs

Where Scientific Innovation, Discovery and Clinical Dermatology Converge

Michael Rosenblum, MD, PhD, was a 20-year-old undergraduate at the University of British Columbia when his mother became ill with breast cancer. At the time, physician-scientists were just beginning to explore how the immune system could be directed to target cancer cells. At the forefront was Dr. Steven Rosenberg, who had written a book that…

Establishment of an Immune-Cell Niche in Skin

Dr. Rosenblum presented his research that identified a novel immune cell niche and its possible clinical applications. First, Dr. Rosenblum discussed regulatory T cells (Tregs) and their role in skin disease. Autoimmune and inflammatory diseases result from disruption in the balance of autoreactive and regulatory cells. Tregs are a type of regulatory cell in the…