pemphigus
Creating Disease Severity and Quality-of-Life Scoring Systems for Blistering Diseases
Comparing the efficacy of existing therapies between clinical trials, as well as evaluating new treatments, requires an accurate and reliable assessment of the clinical nature of a disease. Yet the first comprehensive analysis of the interventions used to treat pemphigus, a range of autoimmune blistering diseases (AIBD), was inconclusive due to incomplete information, including absence…
Dr. Aimee Payne’s Path to Creating CAAR-T Cell Therapies
In 2011, Aimee Payne, MD, PhD, was running a lab at the University of Pennsylvania, studying pemphigus vulgaris, an autoimmune disease of the skin that results when B cells make antibodies that attack the cell-adhesion protein desmoglein 3.