Dr. Jean Bolognia
Mimickers of SJS/TEN
Dr. Jean Bolognia presented information about Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) and diseases that mimic them. SJS and TEN are severe skin reactions that cause damage to the skin and mucus membranes and can be life-threatening. TEN typically involves the entire trunk. First, Bolognia discussed the expanding differential diagnosis of SJS/TEN. Previously, dermatologists would…
Antibody-Drug Conjugates (Chemo-labeled Antibodies)
Dr. Jean Bolognia presented information about antibody-drug conjugates (ADCs), including enfortumab vedotin, trastuzumab emtansine, trastuzumab deruxtecan, and loncastuximab tesirine. ADCs are monoclonal antibodies (mAbs) combined with a chemotherapeutic agent via a linker. They are associated with cutaneous side effects that dermatologists need to know about. First, Bolognia explained the nomenclature of ADCs. The first part…